“Even drugs known for toxicity in cats can be used safely if we are aware of and compensate for certain peculiarities.” That basically says it all. I clean with pine sol and never had a problem with my cats in 12 years. U-40. Some clinicians believe that for dogs, a starting dose of 0.25 U/kg is appropriate and 0.5 U/kg should be reserved for potentially challenging diabetics. Cases of toxicosis in this species are most often the result of inappropriate administration. Vet Rec. Check with your doctor immediately if any of the following side effects occur while taking phenol … Oral median lethal doses (LD 50) for phenol are listed in the HSDB [], Lewis [], and Berman et al. 735) established by the 1999 Joint FAO/WHO Meeting on Pesticide Residues (FAO, 1999). The onset, severity and duration of toxicity is determined by the dose, route of exposure, physicochemical properties of the organophosphate (e.g. Along with its needed effects, phenol topical may cause some unwanted effects. Disinfectant toxicity in cats is summarized in table 1. Berje Inc. Where the world comes to its senses : Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals. 2,6-diisopropyl phenol 2,6-bis(1-methylethyl)phenol Supplier Sponsors. I would like some more info on this. Glargine (long-acting) Product Description. While most cases 2/7. Basically, the higher the concentration of the essential oil (such as one not diffused with carrier oil), the higher the toxicity. Recombinant DNA origin human insulin. Cats are also very sensitive to phenols and phenolic compounds, which can be found in some essential oils. Other data on the toxicity of phenol and its derivatives were consistent with the results of the safety evaluation. Methemoglobinemia and hepatotoxicity characterize acetaminophen toxicosis. depends o n it s arom atic ring where benz ene ring itself . Cats are deficient in an enzyme called glucuronyl transferase, which can be found in the liver and is responsible for breaking down Phenol. Even dilute solutions (1% to 2%) may cause severe burns if contact is prolonged. Top Cat. The symptoms he may display are not commonly seen in anything other than a type of toxicity. Phenol poisoning can occur by skin absorption, vapor inhalation, or ingestion, and, regardless of route of exposure, can result in det rimental health effects. Phenol is both a manufactured chemical and a natural substance. While previous investigations have concluded that in cats the gene for the phenol-type glucuronosyltransferase isoform has turned into a pseudogene because of several point mutations, evaluation of genomic information for snake species revealed that they have only 2 genes that may code for glucuronosyltransferase isoforms. Concentration. And that is 1984! It is a colorless-to-white solid when pure. Acute toxicity (96 h LC50) of phenol was analyzed in the cat fish Mystus vittatus in static bio-assay over a 96-h exposure period using probit method. J Am Vet Med Assoc. Commonly used in cats; not commonly used in dogs. Renal injury is also possible. Examples of such components are phenols. Phenol is caustic to the delicate paw pads. Phenol poisoning in the cat. Primarily, the values are clustered in the range 250–500 mg/kg, although the value Could you direct me to a site. This essential oil is void of phenol and thus certified safe to diffuse around cats. 100%), the greater the risk to the cat. Newer modifications of phenol peels with reduced levels of croton oil have significantly reduced the amount of postoperative hypopigmentation, postoperative erythema, and scarring. When ingested, NSAIDS can result in severe, acute kidney failure (ARF) and gastrointestinal injury/ulcers. Weaker solutions of phenol (25% to 50%) can be used to achieve lighter peels; however, the results are not better than TCA and there is still the risk for systemic toxicity. In the case of cats, poisoning happens by absorption through the skin, although ingestion does happen sometimes. RELEVANT BACKGROUND INFORMATION 2.1 Explanation. Phenol is an aromatic organic compound with the molecular formula C 6 H 5 OH. Then, when cats groom, they ingest the cleaner which damages their liver and kidneys. Treatment in all patients was supportive and symptomatic, and the most commonly used anticonvulsants were diazepam and barbiturates; however, severe unresponsive seizures in three dogs had to be controlled with inhalant gas anaesthesia. It is a white crystalline solid that is volatile. The molecule consists of a phenyl group (−C 6 H 5) bonded to a hydroxy group (−OH). 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